α-Halogenohydrazides: Useful Starting Material for the Synthesis of Hydrazinoazapeptides and Azauracils.

An efficient method for the synthesis of pseudodipeptides, which combines an aza glycine residue with various hydrazinoacid moieties by simple substitution of the halogen of α-halohydrazides, is described. Some of these hydrazinoazapeptides lead to hydrazones by oxidation or to azaaminouracils by cyclization.Key words: hydrazinohydrazides, hydrazones, hydrazinoazapeptides, azaaminouracils, pseudopeptides.