Determining the Physiological Mechanisms Involved in Longer Life Span

Ageing is undoubtedly the most perplexed phenotype occurring among humans. For comprehensive treatment of ageing as well as associated diseases, highly specialized technologies are emerging that reveal critical insight into the underlying mechanisms and giving a novel hope for previously untreated diseases. Previous research has found a link between human social relationships and longevity. In old age, there is a decline in mitochondrial activity as well as changes in nuclear chromatin. Multiple organ failure is connected with animal ageing, but age-related degeneration is the primary component in human ageing. Naked mole-rats with low amounts of circulating methionine survived longer, suggesting they exhibited a natural life-extension phenotype similar to that seen in methionine-restricted animals. A longer life span was achieved as a result of health-improving measures. Humans of various families have variable rates of ageing, and those with exceptional survival offer hope for understanding why some people age more slowly than others.The goal of this study is to discover the most important characteristics that increase longevity. Herein, are described the latest developments in cutting edge technologies applied across the domain of ageing research including the emerging model organisms, high-throughput methodologies and machine-driven approaches. In all, this body of writing will provide you a glimpse of what will be pushing the field upwards and onwards.