Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model

Aurigena Antunes de Araújo,Helicarlos Batista de Morais,Caroline Adisson Carvalho Xavier de Medeiros,Gerly Anne de Castro Brito,Paulo Marcos da Matta Guedes,Sarah Hiyari,Flavia Q. Pirih,Raimundo Fernandes de Araújo Júnior

Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model

2019

Aurigena Antunes de Araújo
Helicarlos Batista de Morais
Caroline Adisson Carvalho Xavier de Medeiros
Gerly Anne de Castro Brito
Paulo Marcos da Matta Guedes
Sarah Hiyari
Flavia Q. Pirih
Raimundo Fernandes de Araújo Júnior

Objective The aim of this study was to evaluate the effects of gliclazide on oxidative stress, inflammation, and bone loss in an experimental periodontal disease model.

Keywords:

Gliclazide
Dentistry
Inflammation
Disease
Materials science
Oxidative stress
Pharmacology
Macrophage migration inhibitory factor
Protein kinase B
Malondialdehyde
RANKL
Cathepsin K
Internal medicine
Endocrinology
Osteoprotegerin

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