A review on synthesis of isoniazid derivatives and their biological properties

Isoniazid is the most important heterocyclic moiety in organic and medicinal chemistry due to the presence of reactive site in the molecule, which extends its application in various fields. Isoniazid is the most important first-line drug used in the treatment of tuberculosis. The interesting molecular design of isoniazid makes them apt moieties in drug design. In this review, our aim is to summarize recent synthetic strategies and pharmacological properties of isoniazid derivatives