PCSK9 INHIBITION AND AORTIC STENOSIS IN THE FOURIER TRIAL

Despite recent advances in treatment of severe aortic valve stenosis (AS), AS remains a common, life-threatening condition with no proven preventive therapy. Low-density lipoprotein cholesterol (LDL-C) and, particularly, lipoprotein(a) (Lp[a]) have been implicated in the pathobiology of AS. The