Multiple C–H Activation Enabled Modular Construction of Densely Functionalized Sulfur-Contained Arenes
2021
Modular construction of multiple
functionalized arenes from abundant feedstocks, stands as an unremitting pursue
goal in synthetic chemistry, which would accelerate the discovery of new drugs
an advanced materials. Herein, by using multiple C-H activation strategy,
through judicious choice of versatile imidate ester as the key directing group,
expedi-ent delivery of molecular libraries of densely functionalized
sulfur-contained arenes. Further synthetic application was demonstrated by
multiple C-H modification of fused arenes and pharmaceuticals such as
Ibuprofen, and concise con-struction of biologically active molecules, Madam
dihydrochloride and Bipenamol, was also achieved.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI