Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population

Takenori Mikami,Akira Meguro,Takeshi Teshigawara,Masaki Takeuchi,Riyo Uemoto,Tatsukata Kawagoe,Eiichi Nomura,Yuri Asukata,Misaki Ishioka,Miki Iwasaki,Kazumi Fukagawa,Kenji Konomi,Jun Shimazaki,Teruo Nishida,Nobuhisa Mizuki

Interleukin 1 beta promoter polymorphism is associated with keratoconus in a Japanese population

2013

Takenori Mikami
Akira Meguro
Takeshi Teshigawara
Masaki Takeuchi
Riyo Uemoto
Tatsukata Kawagoe
Eiichi Nomura
Yuri Asukata
Misaki Ishioka
Miki Iwasaki
Kazumi Fukagawa
Kenji Konomi
Jun Shimazaki
Teruo Nishida
Nobuhisa Mizuki

Purpose Polymorphisms in the interleukin 1 alpha (IL1A) and IL1B gene regions were previously associated with keratoconus in a Korean population. In the present study, we investigated whether the IL1A and IL1B polymorphisms are associated with keratoconus in a Japanese population.

Keywords:

Genetics
Biology
Molecular biology
Linkage disequilibrium
Keratoconus
Allele frequency
Haplotype
IL1A
Polymorphism (computer science)
Interleukin
Population
Alpha (ethology)
Gene

Correction
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