Comportement des oxydes d'ynephosphine et de l'enediynephosphine secondaires en presence d'un milieu biologique : Etudes des activités vis-a-vis del'adn

We describe in this survey the behaviour of ynephosphine oxides in aqueous solution and basic medium. Topics covered include the order of stability related to five different structures of secondary ynephosphine oxides andthe secondary enediynephosphine. Emphasis has been placed on cytotoxic activities with DNA.