Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations.

C. Orellana,Daniel Ferreira,J.-Sebastian Muehlboeck,P. Mecocci,Bruno Vellas,Magdalini Tsolaki,Iwona Kloszewska,H. Soininen,Simon Lovestone,Andrew Simmons,L.-O. Wahlund,Eric Westman

Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations.

2016

C. Orellana
Daniel Ferreira
J.-Sebastian Muehlboeck
P. Mecocci
Bruno Vellas
Magdalini Tsolaki
Iwona Kloszewska
H. Soininen
Simon Lovestone
Andrew Simmons
L.-O. Wahlund
Eric Westman

Background: Global brain atrophy is present in normal aging and different neurodegenerative disorders such as Alzheimer's disease (AD) and is becoming widely used

Keywords:

Pathology
Brain size
Neuroscience
Biology
Alzheimer's disease
Magnetic resonance imaging
Disease
Atrophy
Global brain atrophy
Cerebrospinal fluid
Normative
Confounding
Severity of illness

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