Are women more susceptible than men to iatrogenic inferior alveolar nerve injury in dental implant surgery

An over-representation of women in dental implant-related inferior alveolar nerve injuries (IANIs) is recognized in the literature but has not been investigated. Therefore, a nationwide retrospective register study was conducted to analyse how IANIs compare with other implant-related complications (infection, implant malposition, lack of bone at implant site, mechanical damage, or failed osseointegration) separately in women and men. Financially compensated malpractice claims related to dental implant surgery were collected from the Finnish Patient Insurance Centre for the years 1997-2013, while the total number of nationally placed implants was ascertained from the implant register held by the Finnish Institute for Health and Welfare. In the 242 complications, the following were analysed: age of subject, absolute risk for complication, and aetiological factor of IANI. Statistical tests applied include Mann-Whitney U-test, Chi-squared test, and Fisher's exact test. Women sustaining IANI were more likely older than those having infection, mechanical damage, or failed osseointegration (P<0.05), while no significant differences emerged in men. Women were more likely at risk for IANI (P<0.01) or implant malposition (P<0.05) than men. The results support earlier propositions that women are more vulnerable than men to iatrogenic IANI.