Copper-catalyzed Tandem Aerobic Oxidative Cyclization for the Synthesis of Polysubstituted Quinolines via C(sp3)/C(sp2)-H bonds functionalization
2017
One-pot Cu-catalyzed tandem aerobic oxidative cyclization for the synthesis of quinolines from 2-vinylanilines/2-aryl anilines and 2-methylquinolines via C(sp3)-H/C(sp2)-H bonds functionalization has been developed. Dioxygen as an ideal oxidant has been employed for this transformation. The substrates bearing various functional groups are performed well in this process and generate the desired products in moderate to good yields.
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