Specificity Analysis of DRA Fragments in Core Cell Lines

The polymorphic fragments identified in the core cell lines with the DQA probe and the various restriction enzymes are listed in Table 1. They are identified by enzyme, fragment size, and standard fragment number. The concordance (Con) value shows the reproducibility of the presence or absence of the fragment; 1 indicates no discrepancy for the two pairs of “hidden duplicates” among the DNA samples, 2 a discrepancy for one duplicate pair, 3 a discrepancy for both duplicate pairs, 99 that one or more of the duplicates could not be read for technical reasons. Fragments with similar presence/absence patterns are grouped together in clusters, which are discussed below. Strong antigen correlations are briefly indicated in Table 1; however, the fragment may also be positive (or negative) with DNA of cells not expressing the relevant specificity.