C-glycosylflavones from Stellaria media

AIM: To isolate the chemical constituents from the aerial parts of Stellaria media (L.) Cyr.. METHODS: The compounds were isolated through column chromatography and recrystallization. The structures were elucidated by means of physio-chemical data and spectroscopy. RESULT: Fourteen C-Glycosylflavones were isolated from this plant, and their structures were elucidated as apigenin (1), vicenin (6, 8-di-C-β-D-glucopyranosyl apigenin) (2), 8-C-β-D-galactopyranosyl isovitexin(6-C-β-D-glucopyranosyl-8-C-β-D-galactopyranosyl apigenin) (3), 6-C-β-D-galactopyranosyl vitexin (6-C-β-D-galactopyranosyl-8-C-β-D-glucopyranosyl apigenin) (4), 6, 8-di-C-α-L-arabinopyranosyl apigenin (5), schaftoside (6-C-β-D-glucopyranosyl-8-C-α-L-arabinosyl apigenin) (6), isoschaftoside (6-C-α-L -arabinosyl-8-C-β-D-glucopyranosyl apigenin) (7), 6-C-β-D-galactopyranosyl-8-C-α-L-arabinosyl apigenin (8), 8-C-β-D-galactosyl apigenin (9), vitexin (8-C-β-D-glucopyranosyl apigenin) (10), isovitexin (6-C-β-D-glucopyranosyl apigenin) (11), tricetin 6, 8-di-C-β-D-glucopyranosyl (12), tricetin 6-C-α-L-arabinosyl-8-C-β-D-glucopyranosyl (13) and 7-O-β-D-glucopyranosyl-6-C-β-D-6”-acetyl-glucopyranosyl apigenin (14). CONCLUSIONS: Compounds 3~8 and compounds 12 and 13 have been found in the plant for the first time, and compound 14 is a new C-glycosylflavone.