Novel magnesium-serinate compound and use thereof

The present invention relates to a novel magnesium-serinate compound and its use, and more particularly to a novel magnesium-serinate compound which is chelated with a magnesium atom in L-serine and a novel magnesium- centralnervous system diseases, and the like. The novel magnesium-serinate compound obtained from the preparation method of the present invention was confirmed to be composed of ~ 10% magnesium and ~ 90% serine as a result of the instrumental analysis. (500 mg / ml), and it was maintained in the aqueous solution without formation of precipitate. It was also solubilized in phosphate-buffered saline (PBS) solution at ~ 500 mg / ml without precipitate formation at room temperature , Has been found to have properties suitable for administration to the human body as oral and injectable preparations. The compounds have been shown to enhance mitochondrial function and neuronal proliferation by enhancing the rate of oxygen consumption of mitochondria, and / or damage to mitochondrial membrane potential due to oxidative stress and / And showed neuroprotective effect to suppress neuronal death by ER stress , Autonomic spectrum disorders, Down syndrome, Rett syndrome, fragile X syndrome, Alzheimer ' s disease, Parkinson ' s disease, , Huntington's disease and amyotrophic lateral sclerosis, which are very useful for the pharmaceutical industry.