How Did SARS-CoV2/COVID-19 Pandemic Affected Patients with Rheumatic Diseases in Latin America? A Regional Survey from PANLAR

Background/Purpose: Social isolation during SARS-CoV-2/COVID-19 pandemic has undermined follow-up of patients with rheumatic diseases These patients face a critical dilemma between the risk of exposure as a vulnerable population and the need of medical attention During previous pandemics, factors associated with differential behaviors have been identified, including lack of knowledge and perception of risk Knowledge, attitudes, and behaviors studies are used to investigate patterns of community reactions to a disease The aim of this study was to explore the knowledge, attitudes, and behaviors of patients with rheumatic diseases in Latin America during the COVID-19 pandemic Methods: We performed a cross-sectional observational study by means of a digital anonymous survey (RedCap ®) We included patients over 18 years old from Spanish-speaking PANLAR countries with at least one rheumatic disease (self-reported) We retrieved demographics, comorbidities, rheumatic disease treatment, adherence and self-reported activity prior and during the pandemic, COVID-19 basic knowledge, diagnosis and risk perception, information sources, adherence to precaution measures, impact on daily living, attitudes and behaviors regarding telehealth We calculated median and interquartile range for quantitative variables and frequencies and percentages for qualitative variables Results: Our interim results include 1621 patients from 19 countries The median age is 46 (37-56), most of them are women (92 4%) The most frequent rheumatic diseases were RA (54%) and SLE (26%) Self-reported disease activity increased during the pandemic (35% [8-60] vs 50% [13 5-70]) Twenty-seven (1 7%) responders were diagnosed with COVID-19 Twenty-three percent suspended at least 1 antirheumatic drug, particularly due to unavailability in pharmacies (34 7%);antimalarials were suspended by 22 2% of patients, mainly for the same reason (60 5%) Almost half reported that their follow-up appointments were cancelled and only 29% were offered an alternative Twelve percent received telehealth, mainly via telephone (58%) and video call (34%), with a median satisfaction of 90% (62 5-100) Although 84% of responders consider telehealth as a valid strategy during the pandemic, this proportion reduces to 53 9% as a hypothetical alternative after the pandemic An adequate knowledge on COVID-19 was found in 46% The most frequent sources of information were television and social networks Most patients reported a disruption in daily living due to social restrictions Most responders reported an adequate adherence to general precautions Conclusion: Patients with rheumatic diseases in Latin America were negatively affected by the SARS-CoV2/COVID-19 pandemic An increase in self-reported disease activity, a reduction in medication adherence and hurdles for medical follow-up were reported Telehealth is perceived as a valid alternative to in-person consults during the pan-demic Attitudes and behaviors towards general precautions in this vulnerable population are reassuring Our study is still ongoing and we present interim results;it is planned to collect data until July 31th, 2020