Enantioselective synthesis of 4-aminocyclopent-2-ene-1-one from tricyclo[5.2.1.02,6]decenyl enaminones

Abstract An efficient enantioselective synthesis of 4-amino-cyclopent-2-ene-1-one 12 from enaminones 8 and and its diastereomer has been accomplished via a one step electron transfer reduction of the enaminone double bond and concomitant removal of an α-methylbenzyl group, followed by a [4 + 2] cycloreversion strategy.