Carbene insertion into acyl C-H bonds: Rh(III)-catalyzed cross-coupling of 2-aminobenzaldehydes with conjugated enynones

Abstract A rhodium-catalyzed directed acyl C-H bonds carbene insertion reaction of 2-aminobenzaldehydes with conjugated enynones has been realized, affording a series of α-furyl ketone derivatives in moderate to good yields with good functional group tolerance. Carbene migratory insertion is proposed as the key step in this transformation.