Investigation and Practice of Internal Quality Control in Radioimmunoassay

Objective To investigate the application of internal quality control with two control materials in analysis of thyroid hormone by radioimmunoassay(RIA),in order to effectively reduce losing of control in testing results,by which to afford accurate and authentic test information for clinic.Methods Radioimmunoassay was used in this study.Non-fixed value control material which was self-regulated with batch number P20090723 and fixed value control materials from the three venders were used to carry on internal quality control in analysis of thyroid hormone for the working days in the year by RIA.Results The target value and standard uncertainty of fixed value control material was highly in accordance with the intermediate standard value of thyroid hormone.The analysis of the value in table 1 and table 2 demonstrated that there was statistic difference in mean and standard deviation between our laboratory and venders'(P0.05).Conclusions When analysing with any control material,a laboratory should establish its own target value and standard deviation for effective internal quality control,which can make the accurateness of every batch of test could be recurred by higher precision and accuracy.Our laboratory fixed the normal reference ranges of thyroid hormone with non-fixed value control material self-regulated.