Synthesis and in vitro Anticancer and Antitubercular Activity of Diarylpyrazole Ligated Dihydropyrimidines Possessing Lipophilic Carbamoyl Group.

Rama Krishna Yadlapalli,O.P. Chourasia,Kiranmayi Vemuri,Manjula Sritharan,Ramu Sridhar Perali

Synthesis and in vitro Anticancer and Antitubercular Activity of Diarylpyrazole Ligated Dihydropyrimidines Possessing Lipophilic Carbamoyl Group.

2012

Rama Krishna Yadlapalli
O.P. Chourasia
Kiranmayi Vemuri
Manjula Sritharan
Ramu Sridhar Perali

Utilizing the Biginelli reaction, a series of dihydropyrimidines (IV) is synthesized and evaluated for in vitro anticancer (MCF-7) and antitubercular (MTB) potency.

Keywords:

Potency
Biginelli reaction
In vitro
Chemistry
Organic chemistry

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