An Aggressive Medical-Nutritional Approach to the Management of Refractory Pressure Sores

Ageing is associated with significant changes in body composition: bone mass, lean mass, and water content all decrease, while fat mass increases. The basal metabolic rate, which is closely related to physical activity, is the principal component of total energy expenditure. Reduced basal metabolic rate in older persons reflects the loss of muscle mass resulting in decreased strength and functionality.