Three-dimensional integrated microchemical reaction device applicable to mixing and disruption of cells

The invention discloses a three-dimensional integrated microchemical reaction device applicable to the mixing and the disruption of cells. The three-dimensional integrated microchemical reaction device applicable to the mixing and the disruption of the cells comprises an upper cover plate and a lower cover plate, wherein the upper cover plate cooperates with the lower cover plate up and down; the center of the upper cover plate is provided with a reaction chamber which is completely through; the reaction chamber is communicated with a reaction liquid inlet and a reaction fluid outlet, which are perpendicular to the side surface of the reaction chamber; the upper surface of the upper cover plate is provided with a graphene lower interlayer in a bonding manner; the upper surface of the graphene lower interlayer is provided with a temperature measurement plate in the bonding manner; the center of the temperature measurement plate is provided with a temperature measurement chamber which is completely through; the temperature measurement chamber is communicated with a fluorescent liquid inlet-outlet perpendicular to the side surface of the temperature measurement chamber; the upper surface of the temperature measurement plate is provided with a graphene upper interlayer in the bonding manner; the lower surface of the upper cover plate is provided with a surface acoustic wave generation structure, a micro temperature control structure and a gasket; the lower surface of the gasket is bonded with the upper surface of a lower bottom plate; the lower bottom plate and the upper cover plate are completely same in structure, and are longitudinally symmetrical relative to the gasket. By using the three-dimensional integrated microchemical reaction device applicable to the mixing and the disruption of the cells, the mixing of reaction liquids and the carrying out of a reaction can be promoted; a temperature can be quickly and accurately controlled; the reaction is greatly promoted.