On spatial molecular arrangements of SARS-CoV2 genomes of Indian patients

A pandemic caused by severe acute respiratory syndrome coronavirus-2(SARSCoV2) is being experienced by the whole world since December, 2019. A thorough understanding beyond just sequential similarities among the protein coding genes of SARS-CoV2 is important in order to differentiate or relate to the other known CoVs of the same genus. In this study, three genomes namely MT012098 (India-Kerala), MT050493 (India-Kerala), MT358637 (India-Gujrat) from India and another one NC 045512 (China-Wuhan) as a reference genome from China are considered to view the spatial as well as molecular arrangements of nucleotide bases of all the genes embedded in these four genomes. Based on different features extracted for each genes embedded in these genomes, corresponding phylogenetic relationships have been built up. This study would help to understand the virulence factors, disease athogenicity, origin and transmission of the SARS-CoV2.