Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA (KeraRT), for Corneal Stroma and Tendon Research

Yujin Zhang,Winston W-Y. Kao,Yasuhito Hayashi,Lingling Zhang,Mindy K. Call,Fei Dong,Yong Yuan,Jianhua Zhang,Yen-Chiao Wang,Okada Yuka,Atsushi Shiraishi,Chia yang Liu

Generation and Characterization of a Novel Mouse Line, Keratocan-rtTA (KeraRT), for Corneal Stroma and Tendon Research

2017

Yujin Zhang
Winston W-Y. Kao
Yasuhito Hayashi
Lingling Zhang
Mindy K. Call
Fei Dong
Yong Yuan
Jianhua Zhang
Yen-Chiao Wang
Okada Yuka
Atsushi Shiraishi
Chia yang Liu

Purpose We created a novel inducible mouse line Keratocan-rtTA (KeraRT) that allows specific genetic modification in corneal keratocytes and tenocytes during development and in adults.

Keywords:

Anatomy
Stroma
Tendon
Keratocan
Biology
Cornea
Cell biology
Green fluorescent protein
Ectopic expression
Genetically modified mouse
Gene targeting
Corneal epithelium

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