Thermodynamic and Kinetic Investigation on the Crucial Factors Affecting Adefovir Dipivoxil-Saccharin Cocrystallization

Kun Ma,Ying Zhang,Hongliang Kan,Linfeng Cheng,Ling Luo,Qing Su,Jing Gao,Yuan Gao,Jianjun Zhang

Thermodynamic and Kinetic Investigation on the Crucial Factors Affecting Adefovir Dipivoxil-Saccharin Cocrystallization

2014

Kun Ma
Ying Zhang
Hongliang Kan
Linfeng Cheng
Ling Luo
Qing Su
Jing Gao
Yuan Gao
Jianjun Zhang

Purpose The aim of this study was to perform a thermodynamic and kinetic investigation on the crucial factors affecting the cocrystallization between adefovir dipivoxil (AD) and saccharin (SAC).

Keywords:

Adefovir
Nucleation
Cocrystal
Saccharin
Inorganic chemistry
Chemistry
Stereochemistry
Chromatography
pharmacology toxicology
Computational chemistry
Kinetics

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