Improved antigen cross-presentation by polyethyleneimine-based nanoparticles.

Jian Chen,Zhengrong Li,Hong Huang,Yanzhu Yang,Qian Ding,Junhua Mai,Wei Guo,Yuhong Xu

Improved antigen cross-presentation by polyethyleneimine-based nanoparticles.

2011

Jian Chen
Zhengrong Li
Hong Huang
Yanzhu Yang
Qian Ding
Junhua Mai
Wei Guo
Yuhong Xu

Purpose In the development of therapeutic vaccines against cancer, it is important to design strategies for antigen cross-presentation to stimulate cell-mediated immune responses against tumor antigens.

Keywords:

Molecular biology
Cancer
Immune system
Interleukin 2
Immunology
Antigen
Cross-priming
Cross-presentation
Biology
Major histocompatibility complex
Dendritic cell
Antigen presentation
MHC class I

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