Protective effect of adsorbent complex on morphofunctional state of liver during chicken polymycotoxicosis

The presence of mycotoxins in food can lead to pathological effects ranging from acute intoxication to the effects of chronic exposure (such as carcinogenic, mutagenic, teratogenic) in both humans and animals. Mycotoxins are also a major problem in poultry farming and have harmful effects on birds. The experiment was conducted to determine the effect of adsorbents (shungite/zeolite/glucans 0.5% of the diet) added to a birds diet contaminated with mycotoxins on liver enzyme activity, liver weight and histological characteristics, and the antioxidant system. In experiment 60 Cobb 500 broilers of both sexes, divided into three equal groups (20 chicks in each group), live weight of 650-780 g were used. The experimental period was 20 days. The results showed that the addition of a complex of inorganic and organic adsorbents minimized the pathological effect of zearalenone, aflatoxin B1 and T-2 toxin on the liver and the level of enzymes such as alanine transferase (ALT) and aspartate transferase (AST), and also contributed to the reduction of malone dialdehyde levels relative to the toxic control group. Thus, use of a complex of adsorbents offered by us is an effective and ecologically pure strategy of mycotoxin detoxication in protection of the end-user of animal production - the person.