Asymmetric Synthesis of Cyclopropyl-Fused 2′-C-Methylcarbanucleosides as Potential anti-HCV Agents

Novel 2 ′-C-methyl-cyclopropyl-fused carbocyclic nucleosides as potential anti-HCV agents were stereoselectively synthesized, utilizing regioselective cleavage of the isopropylidene group and cyclic sulfate chemistry as key steps.