The intrinsically disordered region of the cytokinetic F-BAR protein Cdc15 provides a unique essential function in maintenance of cytokinetic ring integrity

Cdc15’s F-BAR domain can be exchanged with other F-BAR domains, but Cdc15’s intrinsically disordered region (IDR) cannot. Deleting part of the IDR results in fragile CRs and reduced calcineurin at ...