Mechanism of myeloid differentiation factor 88 in tumor

Myeloid differentiation factor 88 (MyD88) plays an important role in tumorigenesis, deve-lopment and malignant transformation, also participates in the microenvironment, proliferation, apoptosis, invasion, metastasis and tumor resistance. MyD88 may serve as a new and meaningful therapeutic target, which can promote the growth and development of tumors by regulating multiple signaling pathways and enhance the drug resistance of tumor cells. Key words: Neoplasms; Myeloid differentiation factor 88