One-Pot Synthesis of 3,3'-(4-Arylpyridine-2,6-diyl)bis(2H- chromen-2-one) Derviatives under Microwave Irradiation

A series of 3,3'-(4-arylpyridine-2,6-diyl)bis(2H-chromen-2-one) derviatives were synthesized by the one-pot three-component reaction of 3-acetyl coumarin, aromatic aldehydes, and ammonium acetate in acetic acid under microwave irradiation. The reactions were completed in 5~8 min with 60%~86% yields, and the procedure has the advantages of short reaction time, easy work-up and environmental begin. Their structures were confirmed by H NMR, IR, MS techniques and elemental analysis.