Preparation and Quality Control of Compound Tinidazole Suppository

OBJECTIVE:To prepare the compound tinidazole suppository and establish the quality control standard.METH_ODS:Taking S-40 as the base material and tinidazole,ofloxacin and nigoral as main ingredients,the compound tinidazole suppository was prepared.The UV-spectrophotometry was used for quantitative analysis.RESULTS:The average recovery rates of tinidazole,ofloxacin and nigoral were 98.10%、104.05% and 102.40%and their RSDs were 1.62%、1.33%and 0.68% respectively.CONCLUSION:The preparation of compound tinidazole suppository is easy in technological process.The method of content determination is simple and accurate.