One kind of amino acid salt of atorvastatin

The present invention relates to an amino acid salt of atorvastatin, atorvastatin is reacted with a basic amino acid to give such compounds, methods for their preparation: ⑴ weighed atorvastatin acid, is dissolved in a C1-C6 alcohol solvent, water or a halogenated hydrocarbon solvent, dissolved to form a solution a; ⑵ basic amino acid was weighed, dissolved in an alcohol solvent or water and a C1-C6, dissolved to form a solution b; ⑶ acetate solution was added the above solution a, the mixed solution began to clarify the the mother liquor precipitated crystals, i.e. acid salt of atorvastatin. Amino acid salts of atorvastatin prepared in the present invention not only has the effect of treatment of high cholesterol and blood lipids combined hyperlipidemia, but also has the function to increase amino acid, such as arginine for protection of liver function, so the invention salts effectively compensate for deficiencies known side effects of calcium, potassium and sodium salt of liver damage.