Production and purification of Scandium-47: A potential radioisotope for cancer theranostics

Abstract In this study, production of 47 Sc radionuclide by irradiating the natural titanium dioxide powder (TiO 2 ) in the fast neutron flux (~3*10 13  n cm −2  s −1 ) for 4 days in Tehran Research Reactor (TRR, Iran) and separation from titanium target was investigated. The study showed the feasibility of production 47 Sc by TRR. The separation efficiency and radiochemical purity (ScCl 3 ) of radio-scandium, 47 Sc radionuclide purity were obtained 98%, 99% and 88% respectively.