Mechanism and Origin of Ligand-Controlled Chemo- and Regioselectivity in Palladium-Catalyzed Methoxycarbonylation of Alkynes.

Pd-catalyzed alkoxycarbonylation of alkynes provided a redox-neutral method to selectively access branched/leaner α,β-unsaturated monoesters and 1,4-dicarboxylic acid diesters. Herein, a systematic...