TBHP-Induced Iodocyclization with I2: Atom Economic Synthesis of Iodinated Isoxazolines in Water under Mild Conditions
2019
An efficient intramolecular iodooxygenation of unsaturated ketoximes has been achieved through the activation of iodine by TBHP, yielding various types of synthetically versatile iodinated isoxazolines. This potentially general method is featured by its high atom economy, significant organic waste reduction, and mild reaction conditions.
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