Epidermal growth factor receptor III variant and targeted therapy of glioblastoma

Epidermal growth factor receptor Ⅲ variant (EGFRv Ⅲ ) is high expressed in gliomas,which can be used as a target to treat cancer.The therapy methods of glioblastoma targeted for EGFRv Ⅲ include RNA interference,immunotherapy,etc. Key words: Receptor, epidermal growth factor; Glioma; Molecular targeted therapy