XRCC2-Deficient Cells are Highly Sensitive to 5-Fluorouracil in Colorectal Cancer

Yongzhou Zhang,Jihong An,Yuxin Liu,Xianchuang Wu,Shan Shan Han,Xue-Qun Ren,Chang-Jiang Qin

XRCC2-Deficient Cells are Highly Sensitive to 5-Fluorouracil in Colorectal Cancer

2017

Yongzhou Zhang
Jihong An
Yuxin Liu
Xianchuang Wu
Shan Shan Han
Xue-Qun Ren
Chang-Jiang Qin

Background/Aims: Inhibition of the repair of 5-fluorouracil (5-FU)-induced DNA lesions may improve the responses of tumors to anticancer agents. XRCC2 is a key fa

Keywords:

XRCC2
Fluorouracil
Colorectal cancer
Cancer research
DNA
Biology
Chemotherapy
Lymph node
Apoptosis
Cell growth
DNA repair
Gene knockdown
Biochemistry
Cell cycle

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