In vivo metabolism of SALATRIM fats in the rat : A potential low-calorie fat substitute

SALATRIM fats are structured triacylglycerols that contain at least one short-chain fatty acid (SCFA) and a saturated long-chain fatty acid, usually stearic. SALATRIM 14 C-labeled in either acetate, propionate, stearate, or glycerol and triolein 14 C-labeled in either oleate or glycerol were administered to male rats by gavage. Rats were fed basal diet or basal diet containing 10% (w/w) SALATRIM 23CA lot A014 for 14 days before administration of radiolabeled fats. Acetate and propionate from SALATRIM are rapidly converted to carbon dioxide, which indicates the triacylglycerols are cleaved by lipases in the stomach and upper small intestine