Age-related peculiarities of dynamic structure of wave of the human arterial blood pressure

A decrease of elasticity of walls of aorta and large arteries in the process of human natural aging leads to a significant increment of pulse arterial pressure (AP) due to a reflected wave and accordingly to a rise of the load on myocardium and arterial walls. Therefore, an enhancement of the arterial wall stiffness is considered as a possible mechanism and at the same time as a prognostic factor of risk of development of diseases of the cardiovascular system (CVS). For detection and quantitative estimation of this factor, we applied method of arterial piezopulsometry that allows revealing characteristic age-related peculiarities of the dynamic structure of AP pulse waves, which were used at development of the way and algorithm of express-diagnostics of the functional state of the human CVS. The perspective use of this method for detection of signs of the age-related CVS readjustment as a factor of the organism aging is discussed.