Detection of VIM-2 Metallo-β-Lactamase in Pseudomonas aeruginosa from Germany

The emergence of metallo-β-lactamase (MBL)-producing pathogens is an increasing therapeutic problem. These enzymes have a broad-substrate spectrum; they hydrolyze all β-lactams except for the monobactam aztreonam. At the present time, there is no clinically useful inhibitor available. Four