Somatic embryogenesis critical initiation stage‐specific mCHH hypomethylation reveals epigenetic basis underlying embryogenic redifferentiation in cotton

: As a notable illustration of totipotency, somatic embryogenesis (SE) is the developmental reprogramming of somatic cells toward the embryogenesis pathway (Yang and Zhang, 2010). Investigations examining the totipotency process are of great fundamental and practical importance in crop biotechnology. Moreover, high-frequency regeneration of SE has been limited due to the genotype-dependent response. To date, the epigenetic molecular basis underlying embryogenic redifferentiation during SE remains largely unexplored.