Part of beneficial host response

Fowler comments on the value of a raised temperature to combat flu.1 Fever may also be necessary for optimal defence against bacterial infections.2 We explored this possibility for meningococcal disease. We diluted a suspension of an isolate of Neisseria meningitidis B to approximately 109 colony forming units/ml. We inoculated 500 µl suspension into supplemented proteose peptone 9.5 ml in duplicate and incubated one tube of …