A novel route for C-N coupling reaction: Alternative synthesis of 2-N-benzylaminoquinoline-3-carbonitrile in aqueous media

The present work relates to a process for C-N Coupling which can be used in a variety of chemical reactions. Work provides a process for C-N coupling between aryl halide and aliphatic amines also a low-cost process for C-N Coupling. It is to develop a process for C-N coupling that explores Buchwald-Hartwig amination reaction. Process may use for making N-alkylaminoquinoline which has industrial applications as a ligand.