Synthesis of substituted diazino[c]quinolin-5(6H)-ones, diazino[c]isoquinolin-6(5H)-ones, diazino[c]naphthyridin-6(5H)-ones and diazino[c]naphthyridin-5(6H)-ones

Abstract Substituted diazino[ c ]quinolin-5(6 H )-ones and -isoquinolin-6(5 H )-ones, diazino[ c ]naphthyridin-6(5 H )- and -5(6 H )-ones were obtained using two synthetic routes: one-pot cross-coupling/cyclisation and two-step cross-coupling/KOH-mediated anionic ring closure. The two strategies gave yields in the same order of magnitude and their choice depends on the availability of the starting material.