以香豆素之衍生物作為高選擇性硫醇及銅 (II) 離子螢光化學感測分子之合成與應用

In this thesis, coumarin was used as a signal unit for chemosensors AC and PHC. Chemosensor AC indicates the presence of cysteine and homocysteine among other amino acids with high selectivity by a significant blue emission. Chemosensor AC displays good sensitivity in buffer solution at the pH value 6.0 to 9.0. The detection limits of AC for cysteine and homocysteine are 65 and 78 nM, respectively. In addition, chemosensor AC can be used as a fluorescent probe for detecting cysteine and homocysteine in living cells. Chemosensor PHC indicates the presence of copper ions among other amino acids with high selectivity by a significant blue emission. The detection limit of PHC for Cu (II) is 8 nM. In addition, chemosensor PHC can be used as a fluorescent probe for detecting Cu (II) in living cells.