New Chiral Stationary Phases with Two Chiral Centers for the Liquid Chromatographic Resolution of Racemic Anti-inflammatory Drugs Related to α-Arylpropionic Acids

1994 
New chiral stationary phases (CSPs) with two chiral centers were prepared from (R)- or (S)-α-naphthylethylamine and (S)-naproxen. The (R,S)-CSP prepared from (R)-α-naphthylethylamine and (S)-naproxen was found to be very successful in resolving 3,5-dinitroanilide derivatives of anti-inflammatory drugs related to α-arylpropionic acids.
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