Recent advances in the synthesis of fluorinated compounds via an aryne intermediate.

The development of new methodologies for the synthesis of fluorinated organic molecules is highly demanding due to their wide applications in agriculture and pharmaceutical sciences. Various strategies have been employed in this purpose for a long time. Aryne is well known synthetic intermediate and has gained the attraction of the synthetic chemists for the synthesis of various functionalized organic molecules. Consequently, this synthetic intermediate has been successfully employed in the synthesis of fluorinated organic moieties. Various useful fluorinated aromatic as well as heterocyclic molecules have been synthesized employing aryne intermediate. In this review, we will discuss all these methodologies developed in the last decade via aryne intermediate.