Novel Pt(IV) Pro-drugs Displaying Antimitochondrial Effects.

Leila Tabrizi,Kerry Thompson,Katarzyna Mnich,Chetan Chintha,Adrienne M. Gorman,Liam Morrison,Janna Luessing,Noel F. Lowndes,Peter Dockery,Afshin Samali,Andrea Erxleben

Novel Pt(IV) Pro-drugs Displaying Antimitochondrial Effects.

2020

Leila Tabrizi
Kerry Thompson
Katarzyna Mnich
Chetan Chintha
Adrienne M. Gorman
Liam Morrison
Janna Luessing
Noel F. Lowndes
Peter Dockery
Afshin Samali
Andrea Erxleben

The design, synthesis, characterization and biological activity of a series of platinum(IV) pro-drugs containing the axial ligand 3-(4-phenylquinazoline-2-carboxamido)propanoate (L3) are reported. ...

Keywords:

Biological activity
Biochemistry
Prodrug
Stereochemistry
Chemistry
Platinum
Ligand

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