Biological Sample Preparation System Using Pressure Cycling Technology (PCT)

2003 
Boston Biomedica Inc., (BBI) has developed a proprietary Pressure Cycling Technology (PCT) based Sample Preparation System (PCT SPS) that utilizes a specially designed instrument (BarocyclerTM) and reaction containers (PULSETM Tubes) to apply cycles of hydrostatic pressure to samples. The initial application of the PCT SPS is to liberate molecules from a variety of biological samples, including animal and plant tissues, microbes, and cultured cells. The typical extraction process is accomplished in five minutes or less with as few as five cycles of pressure ranging between atmospheric and 235 MPa. The lysate can then be withdrawn from the PULSE Tubes for downstream analysis, further processing or storage for future use. This System is suitable for genomic and proteomic applications.
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