Dentin Hypersensitivity Efficacy of a Dentifrice with Arginine/Calcium Carbonate

Summary of the Results of Four 8-Week Clinical Studies Assessing the Efficacy in Reducing DentinHypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride Baseline-Adjusted Baseline-AdjustedMean Tactile Sensitivity Scores Mean Air Blast Sensitivity ScoresReference Products Tested N 2 Weeks 4 Weeks 8 Weeks 2 Weeks 4 Weeks 8 WeeksAyad F, et al ., 2009 27 Test toothpaste a 38 23.12* 36.21* 47.34* 1.86* 1.09* 0.34*Positive Control b 39 19.90 29.59 39.00 2.22 1.54 0.93Docimo R, et al ., 2009 28 Test Toothpaste a 40 26.45* 40.98* 45.40* 1.65* 0.92* 0.49*Positive Control b 40 19.30 31.52 40.47 2.17 1.35 0.69Docimo R, et al ., 2009 29 Test Toothpaste a 40 25.87* 40.75* 45.63* 1.59* 0.89* 0.45*Positive Control c 40 18.63 31.62 40.88 1.91 1.21 0.68Que K, et al ., 2010 30 Test Toothpaste d 40 36.50** 45.50** 48.50** 1.18** 0.75** 0.44**Positive Control a 40 35.75** 44.62** 48.00** 1.16** 0.76** 0.38**Negative Control e 41 22.20 26.59 30.12 1.99 1.82 1.72